Development and characterization of nanobodies that specifically target the oncogenic Phosphatase of Regenerating Liver-3 (PRL-3) and impact its interaction with a known binding partner, CNNM3

Phosphatase of Regenerating Liver-3 (PRL-3) is associated with cancer progression and metastasis. The mechanisms that drive PRL-3’s oncogenic functions are not well understood, partly due to a lack of research tools available to study this protein. We have begun to address these issues by developing...

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Detalles Bibliográficos
Autores principales: Smith, Caroline N., Kihn, Kyle, Williamson, Zachary A., Chow, K. Martin, Hersh, Louis B., Korotkov, Konstantin V., Deredge, Daniel, Blackburn, Jessica S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10204944/
https://www.ncbi.nlm.nih.gov/pubmed/37220097
http://dx.doi.org/10.1371/journal.pone.0285964

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10204944/
https://www.ncbi.nlm.nih.gov/pubmed/37220097
http://dx.doi.org/10.1371/journal.pone.0285964

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