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α-Hemolysin promotes uropathogenic E. coli persistence in bladder epithelial cells via abrogating bacteria-harboring lysosome acidification

There is a growing consensus that a significant proportion of recurrent urinary tract infections are linked to the persistence of uropathogens within the urinary tract and their re-emergence upon the conclusion of antibiotic treatment. Studies in mice and human have revealed that uropathogenic Esche...

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Detalles Bibliográficos
Autores principales: Naskar, Manisha, Parekh, Viraj P., Abraham, Mathew A., Alibasic, Zehra, Kim, Min Jung, Suk, Gyeongseo, Noh, Joo Hwan, Ko, Kwan Young, Lee, Joonha, Kim, Chungho, Yoon, Hana, Abraham, Soman N., Choi, Hae Woong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10204954/
https://www.ncbi.nlm.nih.gov/pubmed/37167325
http://dx.doi.org/10.1371/journal.ppat.1011388