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Hypoxia extends lifespan and neurological function in a mouse model of aging

There is widespread interest in identifying interventions that extend healthy lifespan. Chronic continuous hypoxia delays the onset of replicative senescence in cultured cells and extends lifespan in yeast, nematodes, and fruit flies. Here, we asked whether chronic continuous hypoxia is beneficial i...

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Detalles Bibliográficos
Autores principales: Rogers, Robert S., Wang, Hong, Durham, Timothy J., Stefely, Jonathan A., Owiti, Norah A., Markhard, Andrew L., Sandler, Lev, To, Tsz-Leung, Mootha, Vamsi K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10204955/
https://www.ncbi.nlm.nih.gov/pubmed/37220109
http://dx.doi.org/10.1371/journal.pbio.3002117