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DNA supercoiling restricts the transcriptional bursting of neighboring eukaryotic genes
DNA supercoiling has emerged as a major contributor to gene regulation in bacteria, but how DNA supercoiling impacts transcription dynamics in eukaryotes is unclear. Here, using single-molecule dual-color nascent transcription imaging in budding yeast, we show that transcriptional bursting of diverg...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cell Press
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10205079/ https://www.ncbi.nlm.nih.gov/pubmed/37207624 http://dx.doi.org/10.1016/j.molcel.2023.04.015 |