Wernicke encephalopathy revealed by areflexic flaccid tetraparesis associated with gravidarum hyperemesis

Wernicke’s encephalopathy is an acute neuropsychiatric syndrome resulting from thiamine deficiency, which is associated with significant morbidity and mortality. The diagnosis of Wernicke’s encephalopathy is based on the clinical manifestations and rapid reversal of symptoms with thiamine. CASE PRES...

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Autores principales: Ben Chaib, Rajae, Mekkaoui, Ikram, Chetouani, Zaima, kaba, Ousmane, Markaoui, Ikam, Elmezzeoui, Sanae, Bkiyar, Houssam, Housni, Brahim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10205360/
https://www.ncbi.nlm.nih.gov/pubmed/37228999
http://dx.doi.org/10.1097/MS9.0000000000000579
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author Ben Chaib, Rajae
Mekkaoui, Ikram
Chetouani, Zaima
kaba, Ousmane
Markaoui, Ikam
Elmezzeoui, Sanae
Bkiyar, Houssam
Housni, Brahim
author_facet Ben Chaib, Rajae
Mekkaoui, Ikram
Chetouani, Zaima
kaba, Ousmane
Markaoui, Ikam
Elmezzeoui, Sanae
Bkiyar, Houssam
Housni, Brahim
author_sort Ben Chaib, Rajae
collection PubMed
description Wernicke’s encephalopathy is an acute neuropsychiatric syndrome resulting from thiamine deficiency, which is associated with significant morbidity and mortality. The diagnosis of Wernicke’s encephalopathy is based on the clinical manifestations and rapid reversal of symptoms with thiamine. CASE PRESENTATION: The authors present the case of a 25-year-old female patient at the 19th week of gestation (Gravid 1 para 0) with an unremarkable medical history who was admitted to the hospital for an areflexic flaccid tetraparesis with ataxia after persistent vomiting. The brain and spinal MRIs did not reveal any abnormalities, and the evolution was marked by an important improvement after supplementation with thiamine. CONCLUSION: Gayet Wernicke encephalopathy is a medical emergency. Clinical symptoms are inconstant and varied. MRI is the reference examination to confirm the diagnosis, but in 40% of cases it is strictly normal. Early thiamine administration can prevent morbidity and mortality in pregnant women.
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spelling pubmed-102053602023-05-24 Wernicke encephalopathy revealed by areflexic flaccid tetraparesis associated with gravidarum hyperemesis Ben Chaib, Rajae Mekkaoui, Ikram Chetouani, Zaima kaba, Ousmane Markaoui, Ikam Elmezzeoui, Sanae Bkiyar, Houssam Housni, Brahim Ann Med Surg (Lond) Case Reports Wernicke’s encephalopathy is an acute neuropsychiatric syndrome resulting from thiamine deficiency, which is associated with significant morbidity and mortality. The diagnosis of Wernicke’s encephalopathy is based on the clinical manifestations and rapid reversal of symptoms with thiamine. CASE PRESENTATION: The authors present the case of a 25-year-old female patient at the 19th week of gestation (Gravid 1 para 0) with an unremarkable medical history who was admitted to the hospital for an areflexic flaccid tetraparesis with ataxia after persistent vomiting. The brain and spinal MRIs did not reveal any abnormalities, and the evolution was marked by an important improvement after supplementation with thiamine. CONCLUSION: Gayet Wernicke encephalopathy is a medical emergency. Clinical symptoms are inconstant and varied. MRI is the reference examination to confirm the diagnosis, but in 40% of cases it is strictly normal. Early thiamine administration can prevent morbidity and mortality in pregnant women. Lippincott Williams & Wilkins 2023-04-11 /pmc/articles/PMC10205360/ /pubmed/37228999 http://dx.doi.org/10.1097/MS9.0000000000000579 Text en Copyright © 2023 the Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (https://creativecommons.org/licenses/by-nc-nd/4.0/) (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/)
spellingShingle Case Reports
Ben Chaib, Rajae
Mekkaoui, Ikram
Chetouani, Zaima
kaba, Ousmane
Markaoui, Ikam
Elmezzeoui, Sanae
Bkiyar, Houssam
Housni, Brahim
Wernicke encephalopathy revealed by areflexic flaccid tetraparesis associated with gravidarum hyperemesis
title Wernicke encephalopathy revealed by areflexic flaccid tetraparesis associated with gravidarum hyperemesis
title_full Wernicke encephalopathy revealed by areflexic flaccid tetraparesis associated with gravidarum hyperemesis
title_fullStr Wernicke encephalopathy revealed by areflexic flaccid tetraparesis associated with gravidarum hyperemesis
title_full_unstemmed Wernicke encephalopathy revealed by areflexic flaccid tetraparesis associated with gravidarum hyperemesis
title_short Wernicke encephalopathy revealed by areflexic flaccid tetraparesis associated with gravidarum hyperemesis
title_sort wernicke encephalopathy revealed by areflexic flaccid tetraparesis associated with gravidarum hyperemesis
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10205360/
https://www.ncbi.nlm.nih.gov/pubmed/37228999
http://dx.doi.org/10.1097/MS9.0000000000000579
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