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Changes in Protease-Activated Receptor and Trypsin-1 Expression Are Involved in the Therapeutic Effect of Mg(2+) Supplementation in Type 2 Diabetes-Induced Gastric Injury in Male Adult Rats

PURPOSE: Gastric inflammation is common and usually severe in patients with type 2 diabetes mellitus (T2DM). Evidence suggests protease-activated receptors (PARs) are a link between inflammation and gastrointestinal dysfunction. Given that magnesium (Mg(2+)) deficiency is a highly prevalent conditio...

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Detalles Bibliográficos
Autores principales: Mehranfard, Nasrin, Rezazadeh, Hossein, Soltani, Nepton, Dastgerdi, Azadesadat Hosseini, Ghanbari Rad, Mahtab, Ghasemi, Maedeh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10205415/
https://www.ncbi.nlm.nih.gov/pubmed/37228689
http://dx.doi.org/10.1155/2023/5703718