Topological data analysis of protein structure and inter/intra-molecular interaction changes attributable to amino acid mutations

The presence of some amino acid mutations in the amino acid sequence that determines a protein’s structure can significantly affect that 3D structure and its biological function. However, the effects upon structural and functional changes differ for each displaced amino acid, and it is very difficul...

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Detalles Bibliográficos
Autores principales: Koseki, Jun, Hayashi, Shuto, Kojima, Yasuhiro, Hirose, Haruka, Shimamura, Teppei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10205437/
https://www.ncbi.nlm.nih.gov/pubmed/37228703
http://dx.doi.org/10.1016/j.csbj.2023.05.009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10205437/
https://www.ncbi.nlm.nih.gov/pubmed/37228703
http://dx.doi.org/10.1016/j.csbj.2023.05.009

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