PAC1 Deficiency Protects Obese Male Mice From Immobilization-Induced Muscle Atrophy by Suppressing FoxO–Atrogene Axis

Muscle atrophy is the cause and consequence of obesity. Proteasome dysfunction mediates obesity-induced endoplasmic reticulum (ER) stress and insulin resistance in the liver and adipose tissues. However, obesity-associated regulation of proteasome function and its role in the skeletal muscles remain...

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Detalles Bibliográficos
Autores principales: Li, Qifang, Ishii, Kiyo-aki, Kamoshita, Kyoko, Takahashi, Kenta, Abuduwaili, Halimulati, Takayama, Hiroaki, Galicia-Medina, Cynthia M, Tanida, Ryota, Ko Oo, Hein, Gafiyatullina, Guzel, Yao, Xingyu, Abuduyimiti, Tuerdiguli, Hamazaki, Jun, Goto, Hisanori, Nakano, Yujiro, Takeshita, Yumie, Harada, Kenichi, Murata, Shigeo, Takamura, Toshinari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10205472/
https://www.ncbi.nlm.nih.gov/pubmed/37103220
http://dx.doi.org/10.1210/endocr/bqad065

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10205472/
https://www.ncbi.nlm.nih.gov/pubmed/37103220
http://dx.doi.org/10.1210/endocr/bqad065

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