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Molecular mechanisms of amyloid-β peptide fibril and oligomer formation: NMR-based challenges
To completely treat and ultimately prevent dementia, it is essential to elucidate its pathogenic mechanisms in detail. There are two major hypotheses for the pathogenesis of Alzheimer’s dementia: the β-amyloid (Aβ) hypothesis and the tau hypothesis. The modified amyloid hypothesis, which proposes th...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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The Biophysical Society of Japan
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10205579/ https://www.ncbi.nlm.nih.gov/pubmed/37234855 http://dx.doi.org/10.2142/biophysico.bppb-v20.0007 |