Spermidine improves angiogenic capacity of senescent endothelial cells, and enhances ischemia-induced neovascularization in aged mice

Aging is closely associated with the increased morbidity and mortality of ischemic cardiovascular disease, at least partially through impaired angiogenic capacity. Endothelial cells (ECs) play a crucial role in angiogenesis, and their angiogenic capacity declines during aging. Spermidine is a natura...

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Detalles Bibliográficos
Autores principales: Ueno, Daisuke, Ikeda, Koji, Yamazaki, Ekura, Katayama, Akiko, Urata, Ryota, Matoba, Satoaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10205711/
https://www.ncbi.nlm.nih.gov/pubmed/37221395
http://dx.doi.org/10.1038/s41598-023-35447-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10205711/
https://www.ncbi.nlm.nih.gov/pubmed/37221395
http://dx.doi.org/10.1038/s41598-023-35447-3

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