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Establishment of a novel model of endometriosis-associated ovarian cancer by transplanting uterine tissue from Arid1a/Pten knockout mice

Although endometriosis is primarily benign, it has been identified as a risk factor for endometriosis-associated ovarian cancer (EAOC). Genetic alterations in ARID1A, PTEN, and PIK3CA have been reported in EAOC; however, an appropriate EAOC animal model has yet to be established. Therefore, the pres...

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Detalles Bibliográficos
Autores principales: Ono, Motoki, Miyamoto, Tsutomu, Asaka, Ryoichi, Uchikawa, Junko, Ando, Hirofumi, Tanaka, Yasuhiro, Shinagawa, Manaka, Yokokawa, Yusuke, Asaka, Shiho, Wang, Tian-Li, Shih, Ie-Ming, Shiozawa, Tanri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10205720/
https://www.ncbi.nlm.nih.gov/pubmed/37221199
http://dx.doi.org/10.1038/s41598-023-35292-4