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Effective dose window for containing tumor burden under tolerable level

A maximum-tolerated dose (MTD) reduces the drug-sensitive cell population, though it may result in the competitive release of drug resistance. Alternative treatment strategies such as adaptive therapy (AT) or dose modulation aim to impose competitive stress on drug-resistant cell populations by main...

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Detalles Bibliográficos
Autores principales: Masud, M. A., Kim, Jae-Young, Kim, Eunjung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10205748/
https://www.ncbi.nlm.nih.gov/pubmed/37221258
http://dx.doi.org/10.1038/s41540-023-00279-4