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Effective dose window for containing tumor burden under tolerable level
A maximum-tolerated dose (MTD) reduces the drug-sensitive cell population, though it may result in the competitive release of drug resistance. Alternative treatment strategies such as adaptive therapy (AT) or dose modulation aim to impose competitive stress on drug-resistant cell populations by main...
Autores principales: | Masud, M. A., Kim, Jae-Young, Kim, Eunjung |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10205748/ https://www.ncbi.nlm.nih.gov/pubmed/37221258 http://dx.doi.org/10.1038/s41540-023-00279-4 |
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