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Design, synthesis, antitumor evaluation, and molecular docking of novel pyrrolo[2,3-d]pyrimidine as multi-kinase inhibitors
In the last twenty years, protein kinases have been identified as important targets for cancer therapy. In order to prevent unexpected toxicity, medicinal chemists have always focused on discovering selective protein kinase inhibitors. However, cancer is a multifactorial process and its formation an...
主要な著者: | , , , , |
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フォーマット: | Online 論文 テキスト |
言語: | English |
出版事項: |
Elsevier
2023
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主題: | |
オンライン・アクセス: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10205775/ https://www.ncbi.nlm.nih.gov/pubmed/37234342 http://dx.doi.org/10.1016/j.jsps.2023.05.003 |