MBTPS2 acts as a regulator of lipogenesis and cholesterol synthesis through SREBP signalling in prostate cancer

BACKGROUND: Prostate cancer is the most common cancer in men in the developed world, with most deaths caused by advanced and metastatic disease which has no curative options. Here, we identified Mbtps2 alteration to be associated with metastatic disease in an unbiased in vivo screen and demonstrated...

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Detalles Bibliográficos
Autores principales: Tibbo, Amy J., Hartley, Andrew, Vasan, Richa, Shaw, Robin, Galbraith, Laura, Mui, Ernest, Leung, Hing Y., Ahmad, Imran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10205813/
https://www.ncbi.nlm.nih.gov/pubmed/36991255
http://dx.doi.org/10.1038/s41416-023-02237-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10205813/
https://www.ncbi.nlm.nih.gov/pubmed/36991255
http://dx.doi.org/10.1038/s41416-023-02237-7

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