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Platycodin D inhibits the proliferation and migration of hypertrophic scar-derived fibroblasts and promotes apoptosis through a caspase-dependent pathway

Abnormal fibroblast proliferation and excessive extracellular matrix (ECM) deposition lead to the formation of hypertrophic scars (HSs). However, there is no satisfactory method to inhibit the occurrence and development of HSs. In our study, platycodin D (PD), a natural compound extracted from Platy...

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Detalles Bibliográficos
Autores principales: Yu, Zhencheng, Li, Yun, Fu, Rao, Xue, Yaxin, Zhao, Danyang, Han, Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10205854/
https://www.ncbi.nlm.nih.gov/pubmed/36526799
http://dx.doi.org/10.1007/s00403-022-02513-1