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USP13 promotes breast cancer metastasis through FBXL14-induced Twist1 ubiquitination

PURPOSE: Epithelial-to-mesenchymal transition (EMT) is an important cause of high mortality in breast cancer. Twist1 is one of the EMT transcription factors (EMT-TFs) with a noticeably short half-life, which is regulated by proteasome degradation pathways. Recent studies have found that USP13 stabil...

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Detalles Bibliográficos
Autores principales: Zhao, Binggong, Huo, Wei, Yu, Xiaomin, Shi, Xiaoxia, Lv, Linlin, Yang, Yuxi, Kang, Jie, Li, Shujing, Wu, Huijian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10205858/
https://www.ncbi.nlm.nih.gov/pubmed/36732432
http://dx.doi.org/10.1007/s13402-023-00779-9