Discovery and biosynthesis of tricyclic copper-binding ribosomal peptides containing histidine-to-butyrine crosslinks

Cyclic peptide natural products represent an important class of bioactive compounds and clinical drugs. Enzymatic side-chain macrocyclization of ribosomal peptides is a major strategy developed by nature to generate these chemotypes, as exemplified by the superfamily of ribosomally synthesized and p...

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Detalles Bibliográficos
Autores principales: Li, Yuqing, Ma, Yeying, Xia, Yinzheng, Zhang, Tao, Sun, Shuaishuai, Gao, Jiangtao, Yao, Hongwei, Wang, Huan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10206099/
https://www.ncbi.nlm.nih.gov/pubmed/37221219
http://dx.doi.org/10.1038/s41467-023-38517-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10206099/
https://www.ncbi.nlm.nih.gov/pubmed/37221219
http://dx.doi.org/10.1038/s41467-023-38517-2

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