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A graph-based machine learning framework identifies critical properties of FVIII that lead to hemophilia A
Introduction: Blood coagulation is an essential process to cease bleeding in humans and other species. This mechanism is characterized by a molecular cascade of more than a dozen components activated after an injury to a blood vessel. In this process, the coagulation factor VIII (FVIII) is a master...
Autores principales: | Ferreira, Marcos V., Nogueira, Tatiane, Rios, Ricardo A., Lopes, Tiago J. S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10206133/ https://www.ncbi.nlm.nih.gov/pubmed/37235045 http://dx.doi.org/10.3389/fbinf.2023.1152039 |
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