Dynamic change in Siglec-15 expression in peritumoral macrophages confers an immunosuppressive microenvironment and poor outcome in glioma

BACKGROUND: Sialic acid-binding immunoglobulin-like lectin-15 (Siglec-15) was reported to be a novel immune checkpoint molecule comparable to programmed cell death 1 ligand 1 (PD-L1). However, its expression profile and immunosuppressive mechanisms in the glioma tumor microenvironment have not yet b...

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Detalles Bibliográficos
Autores principales: Chen, Quan, Chen, Bingkun, Wang, Chunhua, Hu, Li, Wu, Qiongwen, Zhu, Yanyang, Zhang, Qiuyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10206144/
https://www.ncbi.nlm.nih.gov/pubmed/37234161
http://dx.doi.org/10.3389/fimmu.2023.1159085

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10206144/
https://www.ncbi.nlm.nih.gov/pubmed/37234161
http://dx.doi.org/10.3389/fimmu.2023.1159085

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