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Disruption of the early-life microbiota alters Peyer’s patch development and germinal center formation in gastrointestinal-associated lymphoid tissue

During postnatal development, both the maturing microbiome and the host immune system are susceptible to environmental perturbations such as antibiotic use. The impact of timing in which antibiotic exposure occurs was investigated by treating mice from days 5–9 with amoxicillin or azithromycin, two...

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Detalles Bibliográficos
Autores principales: Borbet, Timothy C., Pawline, Miranda B., Li, Jackie, Ho, Melody L., Yin, Yue Sandra, Zhang, Xiaozhou, Novikova, Ekaterina, Jackson, Katelyn, Mullins, Briana J., Ruiz, Victoria E., Hines, Marcus J., Zhang, Xue-Song, Müller, Anne, Koralov, Sergei B., Blaser, Martin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10206152/
https://www.ncbi.nlm.nih.gov/pubmed/37235047
http://dx.doi.org/10.1016/j.isci.2023.106810