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Disruption of the early-life microbiota alters Peyer’s patch development and germinal center formation in gastrointestinal-associated lymphoid tissue
During postnatal development, both the maturing microbiome and the host immune system are susceptible to environmental perturbations such as antibiotic use. The impact of timing in which antibiotic exposure occurs was investigated by treating mice from days 5–9 with amoxicillin or azithromycin, two...
Autores principales: | Borbet, Timothy C., Pawline, Miranda B., Li, Jackie, Ho, Melody L., Yin, Yue Sandra, Zhang, Xiaozhou, Novikova, Ekaterina, Jackson, Katelyn, Mullins, Briana J., Ruiz, Victoria E., Hines, Marcus J., Zhang, Xue-Song, Müller, Anne, Koralov, Sergei B., Blaser, Martin J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10206152/ https://www.ncbi.nlm.nih.gov/pubmed/37235047 http://dx.doi.org/10.1016/j.isci.2023.106810 |
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