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Transporter proteins knowledge graph construction and its application in drug development

Transporters are the main determinant for pharmacokinetics characteristics of drugs, such as absorption, distribution, and excretion of drugs in humans. However, it is difficult to perform drug transporter validation and structure analysis of membrane transporter proteins by experimental methods. Ma...

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Detalles Bibliográficos
Autores principales: Chen, Xiao-Hui, Ruan, Yao, Liu, Yan-Guang, Duan, Xin-Ya, Jiang, Feng, Tang, Hao, Zhang, Hong-Yu, Zhang, Qing-Ye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10206172/
https://www.ncbi.nlm.nih.gov/pubmed/37235186
http://dx.doi.org/10.1016/j.csbj.2023.05.001