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Transporter proteins knowledge graph construction and its application in drug development
Transporters are the main determinant for pharmacokinetics characteristics of drugs, such as absorption, distribution, and excretion of drugs in humans. However, it is difficult to perform drug transporter validation and structure analysis of membrane transporter proteins by experimental methods. Ma...
Autores principales: | Chen, Xiao-Hui, Ruan, Yao, Liu, Yan-Guang, Duan, Xin-Ya, Jiang, Feng, Tang, Hao, Zhang, Hong-Yu, Zhang, Qing-Ye |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Research Network of Computational and Structural Biotechnology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10206172/ https://www.ncbi.nlm.nih.gov/pubmed/37235186 http://dx.doi.org/10.1016/j.csbj.2023.05.001 |
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