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Daunorubicin resensitizes Gram-negative superbugs to the last-line antibiotics and prevents the transmission of antibiotic resistance

Although meropenem, colistin, and tigecycline are recognized as the last-line antibiotics for multidrug-resistant Gram-negative bacteria (MDR-GN), the emergence of mobile resistance genes such as bla(NDM), mcr, and tet(X) severely compromises their clinical effectiveness. Developing novel antibiotic...

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Detalles Bibliográficos
Autores principales: Cai, Jinju, Deng, Tian, Shi, Jingru, Chen, Chen, Wang, Zhiqiang, Liu, Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10206174/
https://www.ncbi.nlm.nih.gov/pubmed/37235051
http://dx.doi.org/10.1016/j.isci.2023.106809