GTPase splice variants RAC1 and RAC1B display isoform-specific differences in localization, prenylation, and interaction with the chaperone protein SmgGDS

Identifying events that regulate the prenylation and localization of small GTPases will help define new strategies for therapeutic targeting of these proteins in disorders such as cancer, cardiovascular disease, and neurological deficits. Splice variants of the chaperone protein SmgGDS (encoded by R...

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Detalles Bibliográficos
Autores principales: Koehn, Olivia J., Lorimer, Ellen, Unger, Bethany, Harris, Ra’Mal, Das, Akansha S., Suazo, Kiall F., Auger, Shelby A., Distefano, Mark D., Prokop, Jeremy W., Williams, Carol L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10206184/
https://www.ncbi.nlm.nih.gov/pubmed/37059183
http://dx.doi.org/10.1016/j.jbc.2023.104698

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10206184/
https://www.ncbi.nlm.nih.gov/pubmed/37059183
http://dx.doi.org/10.1016/j.jbc.2023.104698

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