Cargando…

Coordination between the Ndc80 complex and dynein is essential for microtubule plus-end capture by kinetochores during early mitosis

Mitotic kinetochores are initially captured by dynamic microtubules via a “search-and-capture” mechanism. The microtubule motor, dynein, is critical for kinetochore capture as it has been shown to transport microtubule-attached chromosomes toward the spindle pole during prometaphase. The microtubule...

Descripción completa

Detalles Bibliográficos
Autores principales: Amin, Mohammed Abdullahel, Chakraborty, Manas, Wallace, Destiny Ariel, Varma, Dileep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10206188/
https://www.ncbi.nlm.nih.gov/pubmed/37060995
http://dx.doi.org/10.1016/j.jbc.2023.104711