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Coordination between the Ndc80 complex and dynein is essential for microtubule plus-end capture by kinetochores during early mitosis
Mitotic kinetochores are initially captured by dynamic microtubules via a “search-and-capture” mechanism. The microtubule motor, dynein, is critical for kinetochore capture as it has been shown to transport microtubule-attached chromosomes toward the spindle pole during prometaphase. The microtubule...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10206188/ https://www.ncbi.nlm.nih.gov/pubmed/37060995 http://dx.doi.org/10.1016/j.jbc.2023.104711 |