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Mitochondrial membrane potential instability on reperfusion after ischemia does not depend on mitochondrial Ca(2+) uptake

Physiologic Ca(2+) entry via the Mitochondrial Calcium Uniporter (MCU) participates in energetic adaption to workload but may also contribute to cell death during ischemia/reperfusion (I/R) injury. The MCU has been identified as the primary mode of Ca(2+) import into mitochondria. Several groups hav...

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Detalles Bibliográficos
Autores principales: Ashok, Deepthi, Papanicolaou, Kyriakos, Sidor, Agnieszka, Wang, Michelle, Solhjoo, Soroosh, Liu, Ting, O’Rourke, Brian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10206190/
https://www.ncbi.nlm.nih.gov/pubmed/37061004
http://dx.doi.org/10.1016/j.jbc.2023.104708