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Synthesis and anticancer activity of podophyllotoxin derivatives with nitrogen-containing heterocycles

Three series of podophyllotoxin derivatives with various nitrogen-containing heterocycles were designed and synthesized. The antitumor activity of these podophyllotoxin derivatives was evaluated in vitro against a panel of human tumor cell lines. The results showed that podophyllotoxin-imidazolium s...

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Detalles Bibliográficos
Autores principales: Yin, Meng, Fang, Yongsheng, Sun, Xiaotong, Xue, Minggao, Zhang, Caimei, Zhu, Zhiyun, Meng, Yamiao, Kong, Lingmei, Myint, Yi Yi, Li, Yan, Zhao, Jingfeng, Yang, Xiaodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10206303/
https://www.ncbi.nlm.nih.gov/pubmed/37234201
http://dx.doi.org/10.3389/fchem.2023.1191498