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TLR4-mediated release of heparin-binding protein in human airways: a co-stimulatory role for IL-26

BACKGROUND: Bacterial infection causes accumulation of neutrophils that release antimicrobial proteins including heparin-binding protein (HBP). In human airways, this neutrophil accumulation can be re-capitulated via intrabronchial exposure to lipopolysaccharide (LPS), a Toll-like receptor 4 (TLR4)...

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Detalles Bibliográficos
Autores principales: Paulsson, Magnus, Cardenas, Eduardo I., Che, Karlhans F., Brundin, Bettina, Smith, Margaretha, Qvarfordt, Ingemar, Lindén, Anders
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10206387/
https://www.ncbi.nlm.nih.gov/pubmed/37234157
http://dx.doi.org/10.3389/fimmu.2023.1178135