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Molecular background of HAC1-driven improvement in the secretion of recombinant protein in Yarrowia lipolytica based on comparative transcriptomics

While the unfolded protein response (UPR) and its major regulator – transcription factor Hac1 are well-conserved across Eukarya, species-specific variations are repeatedly reported. Here we investigated molecular mechanisms by which co-over-expression of HAC1 improves secretion of a recombinant prot...

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Detalles Bibliográficos
Autores principales: Korpys-Woźniak, Paulina, Celińska, Ewelina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10206436/
https://www.ncbi.nlm.nih.gov/pubmed/37234569
http://dx.doi.org/10.1016/j.btre.2023.e00801