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Structure of the transmembrane protein 2 (TMEM2) ectodomain and its apparent lack of hyaluronidase activity

Background: Hyaluronic acid (HA) is a major polysaccharide component of the extracellular matrix. HA has essential functions in tissue architecture and the regulation of cell behaviour. HA turnover needs to be finely balanced. Increased HA degradation is associated with cancer, inflammation, and oth...

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Detalles Bibliográficos
Autores principales: Niu, Muyuan, McGrath, Molly, Sammon, Douglas, Gardner, Scott, Morgan, Rhodri Marc, Di Maio, Antonio, Liu, Yan, Bubeck, Doryen, Hohenester, Erhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10206443/
https://www.ncbi.nlm.nih.gov/pubmed/37234743
http://dx.doi.org/10.12688/wellcomeopenres.18937.2