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Structure of the transmembrane protein 2 (TMEM2) ectodomain and its apparent lack of hyaluronidase activity
Background: Hyaluronic acid (HA) is a major polysaccharide component of the extracellular matrix. HA has essential functions in tissue architecture and the regulation of cell behaviour. HA turnover needs to be finely balanced. Increased HA degradation is associated with cancer, inflammation, and oth...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
F1000 Research Limited
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10206443/ https://www.ncbi.nlm.nih.gov/pubmed/37234743 http://dx.doi.org/10.12688/wellcomeopenres.18937.2 |