Hypoxia-induced loss of SRSF2-dependent DNA methylation promotes CTCF-mediated alternative splicing of VEGFA in breast cancer

Alternative splicing of vascular endothelial growth factor A (VEGFA) generates numerous isoforms with unique roles in tumor angiogenesis, and investigating the underlying mechanism during hypoxia necessitates diligent pursuance. Our research systematically demonstrated that the splicing factor SRSF2...

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Detalles Bibliográficos
Autores principales: Yadav, Pooja, Pandey, Anchala, Kakani, Parik, Mutnuru, Srinivas Abhishek, Samaiya, Atul, Mishra, Jharna, Shukla, Sanjeev
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10206493/
https://www.ncbi.nlm.nih.gov/pubmed/37235058
http://dx.doi.org/10.1016/j.isci.2023.106804

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10206493/
https://www.ncbi.nlm.nih.gov/pubmed/37235058
http://dx.doi.org/10.1016/j.isci.2023.106804

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