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Hypoxia-induced loss of SRSF2-dependent DNA methylation promotes CTCF-mediated alternative splicing of VEGFA in breast cancer

Alternative splicing of vascular endothelial growth factor A (VEGFA) generates numerous isoforms with unique roles in tumor angiogenesis, and investigating the underlying mechanism during hypoxia necessitates diligent pursuance. Our research systematically demonstrated that the splicing factor SRSF2...

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Detalles Bibliográficos
Autores principales:	Yadav, Pooja, Pandey, Anchala, Kakani, Parik, Mutnuru, Srinivas Abhishek, Samaiya, Atul, Mishra, Jharna, Shukla, Sanjeev
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10206493/ https://www.ncbi.nlm.nih.gov/pubmed/37235058 http://dx.doi.org/10.1016/j.isci.2023.106804

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