Integrated analysis revealed hypoxia signatures and LDHA related to tumor cell dedifferentiation and unfavorable prognosis in pancreatic adenocarcinoma: Hypoxia in PDAC

Pancreatic ductal adenocarcinoma (PDAC) is a highly heterogeneous cancer with limited understanding of its classification and tumor microenvironment. Here, by analyzing single-nucleus RNA sequencing of 43, 817 tumor cells from 15 PDAC tumors and non-tumor, we find that hypoxia signatures were hetero...

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Detalles Bibliográficos
Autores principales: Dong, Mingwei, Tang, Rong, Wang, Wei, Xu, Jin, Liu, Jiang, Liang, Chen, Hua, Jie, Meng, Qingcai, Yu, Xianjun, Zhang, Bo, Shi, Si
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10206494/
https://www.ncbi.nlm.nih.gov/pubmed/37182509
http://dx.doi.org/10.1016/j.tranon.2023.101692

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10206494/
https://www.ncbi.nlm.nih.gov/pubmed/37182509
http://dx.doi.org/10.1016/j.tranon.2023.101692

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