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Enhanced mitochondrial fission inhibits triple-negative breast cancer cell migration through an ROS-dependent mechanism

Mitochondria produce reactive oxygen species (ROS), which function in signal transduction. Mitochondrial dynamics, encompassing morphological shifts between fission and fusion, can directly impact ROS levels in cancer cells. In this study, we identified an ROS-dependent mechanism for how enhanced mi...

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Detalles Bibliográficos
Autores principales: Humphries, Brock A., Zhang, Anne, Buschhaus, Johanna M., Bevoor, Avinash, Farfel, Alex, Rajendran, Shrila, Cutter, Alyssa C., Luker, Gary D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10206500/
https://www.ncbi.nlm.nih.gov/pubmed/37235049
http://dx.doi.org/10.1016/j.isci.2023.106788