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Maternal dendritic cells influence fetal allograft response following murine in-utero hematopoietic stem cell transplantation

BACKGROUND: Intrauterine hematopoietic stem cell transplantation (IUT), potentially curative in congenital haematological disease, is often inhibited by deleterious immune responses to donor cells resulting in subtherapeutic donor cell chimerism (DCC). Microchimerism of maternal immune cells (MMc) t...

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Detalles Bibliográficos
Autores principales: Kandasamy, Karthikeyan, Johana, Nuryanti Binti, Tan, Lay Geok, Tan, Yvonne, Yeo, Julie Su Li, Yusof, Nur Nazneen Binte, Li, Zhihui, Koh, Jiayu, Ginhoux, Florent, Chan, Jerry K. Y., Choolani, Mahesh, Mattar, Citra N. Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10206581/
https://www.ncbi.nlm.nih.gov/pubmed/37226255
http://dx.doi.org/10.1186/s13287-023-03366-9