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Developmental and reproductive toxicity of a recombinant protein subunit COVID-19 vaccine (ZF2001) in rats

ZF2001, a protein subunit vaccine against coronavirus disease 2019 (COVID-19), contains recombinant tandem repeat of dimeric receptor-binding domain (RBD) protein of the SARS-CoV-2 spike protein with an aluminium-based adjuvant. During the development of this vaccine, two nonclinical studies were co...

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Detalles Bibliográficos
Autores principales: Song, Yisheng, Shao, Jinjin, She, Guangbiao, Lv, Wanqiang, Chen, Guoyu, Liu, Jing, Zhang, Lili, Zhang, Chengda, Wang, Jiahong, Tian, Ruiyu, Dai, Lianpan, Gao, George F., Huang, Enqi, Zhang, Lijiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10206582/
https://www.ncbi.nlm.nih.gov/pubmed/37225729
http://dx.doi.org/10.1038/s41541-023-00673-3