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Two Distinct Thermodynamic Gradients for Cellular Metalation of Vitamin B(12)
[Image: see text] The acquisition of Co(II) by the corrin component of vitamin B(12) follows one of two distinct pathways, referred to as early or late Co(II) insertion. The late insertion pathway exploits a Co(II) metallochaperone (CobW) from the COG0523 family of G3E GTPases, while the early inser...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10206600/ https://www.ncbi.nlm.nih.gov/pubmed/37234125 http://dx.doi.org/10.1021/jacsau.3c00119 |