Two Distinct Thermodynamic Gradients for Cellular Metalation of Vitamin B(12)

[Image: see text] The acquisition of Co(II) by the corrin component of vitamin B(12) follows one of two distinct pathways, referred to as early or late Co(II) insertion. The late insertion pathway exploits a Co(II) metallochaperone (CobW) from the COG0523 family of G3E GTPases, while the early inser...

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Detalles Bibliográficos
Autores principales: Young, Tessa R., Deery, Evelyne, Foster, Andrew W., Martini, Maria Alessandra, Osman, Deenah, Warren, Martin J., Robinson, Nigel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10206600/
https://www.ncbi.nlm.nih.gov/pubmed/37234125
http://dx.doi.org/10.1021/jacsau.3c00119

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