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Decreasing microtubule detyrosination by parthenolide restores sodium current in mdx cardiomyocytes
FUNDING ACKNOWLEDGEMENTS: Type of funding sources: None. BACKGROUND: The cardiac sodium channel Nav1.5 is transported to the membrane by the microtubule network. Alterations in microtubule dynamics are known to impact on ion channel trafficking. Pathophysiological conditions such as heart failure an...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10207065/ http://dx.doi.org/10.1093/europace/euad122.592 |