Dual inhibition of IDO1/TDO2 enhances anti-tumor immunity in platinum-resistant non-small cell lung cancer

BACKGROUND: The impact of non-small cell lung cancer (NSCLC) metabolism on the immune microenvironment is not well understood within platinum resistance. We have identified crucial metabolic differences between cisplatin-resistant (CR) and cisplatin-sensitive (CS) NSCLC cells with elevated indoleami...

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Detalles Bibliográficos
Autores principales: Wu, Chunjing, Spector, Sydney A., Theodoropoulos, George, Nguyen, Dan J. M., Kim, Emily Y., Garcia, Ashley, Savaraj, Niramol, Lim, Diane C., Paul, Ankita, Feun, Lynn G., Bickerdike, Michael, Wangpaichitr, Medhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10207715/
https://www.ncbi.nlm.nih.gov/pubmed/37226257
http://dx.doi.org/10.1186/s40170-023-00307-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10207715/
https://www.ncbi.nlm.nih.gov/pubmed/37226257
http://dx.doi.org/10.1186/s40170-023-00307-1

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