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Hypertension, antihypertensive drugs, and age at onset of Huntington’s disease

BACKGROUND: Associations between blood pressure (BP) with age at onset of Huntington’s disease (HD) have reported inconsistent findings. We used Mendelian randomization (MR) to assess effects of BP and lowering systolic BP (SBP) via the genes encoding targets of antihypertensive drugs on age at onse...

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Detalles Bibliográficos
Autores principales: Zhu, Yahui, Li, Mao, Bai, Jiongming, Wang, Haoran, Huang, Xusheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10207760/
https://www.ncbi.nlm.nih.gov/pubmed/37226269
http://dx.doi.org/10.1186/s13023-023-02734-1