Synergistic inter-clonal cooperation involving crosstalk, co-option and co-dependency can enhance the invasiveness of genetically distant cancer clones

BACKGROUND: Despite intensive research, cancer remains a major health problem. The difficulties in treating cancer reflect the complex nature of this disease, including high levels of heterogeneity within tumours. Intra-tumour heterogeneity creates the conditions for inter-clonal competition and sel...

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Detalles Bibliográficos
Autores principales: Carneiro, Caroline S., Hapeman, Jorian D., Nedelcu, Aurora M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10207807/
https://www.ncbi.nlm.nih.gov/pubmed/37226092
http://dx.doi.org/10.1186/s12862-023-02129-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10207807/
https://www.ncbi.nlm.nih.gov/pubmed/37226092
http://dx.doi.org/10.1186/s12862-023-02129-7

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