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Oral antibiotics lower mycophenolate mofetil drug exposure, possibly by interfering with the enterohepatic recirculation: A case series

Mycophenolate mofetil has an important role as immunosuppressive agent in solid organ transplant recipients. Exposure to the active mycophenolic acid (MPA) can be monitored using therapeutic drug monitoring. We present three cases in which MPA exposure severely decreased after oral antibiotic coadmi...

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Detalles Bibliográficos
Autores principales: Simoons, Mirjam, Naipal, Kishan A. T., de Jong, Huib, den Hoed, Caroline M., de Winter, Brenda C. M., Mulder, Midas B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10207934/
https://www.ncbi.nlm.nih.gov/pubmed/37222485
http://dx.doi.org/10.1002/prp2.1103