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cGAS regulates the DNA damage response to maintain proliferative signaling in gastric cancer cells
The activation of some oncogenes promote cancer cell proliferation and growth, facilitate cancer progression and metastasis by induce DNA replication stress, even genome instability. Activation of the cyclic GMP-AMP synthase (cGAS) mediates classical DNA sensing, is involved in genome instability, a...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Tech Science Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10208015/ https://www.ncbi.nlm.nih.gov/pubmed/37305397 http://dx.doi.org/10.32604/or.2022.03529 |