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cGAS regulates the DNA damage response to maintain proliferative signaling in gastric cancer cells

The activation of some oncogenes promote cancer cell proliferation and growth, facilitate cancer progression and metastasis by induce DNA replication stress, even genome instability. Activation of the cyclic GMP-AMP synthase (cGAS) mediates classical DNA sensing, is involved in genome instability, a...

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Detalles Bibliográficos
Autores principales: LIU, BIN, LIU, HAIPENG, REN, FEIFEI, LIU, HANGFAN, BUKHARI, IHTISHAM, FU, YUMING, WU, WANQING, ZHAO, MINGHAI, ZHU, SHAOGONG, MO, HUI, LI, FAZHAN, ZHENG, MICHAEL B., TANG, YOUCAI, ZHENG, PENGYUAN, MI, YANG
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tech Science Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10208015/
https://www.ncbi.nlm.nih.gov/pubmed/37305397
http://dx.doi.org/10.32604/or.2022.03529