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Visualization of the three-dimensional structure of the human centromere in mitotic chromosomes by superresolution microscopy
The human centromere comprises large arrays of repetitive α-satellite DNA at the primary constriction of mitotic chromosomes. In addition, centromeres are epigenetically specified by the centromere-specific histone H3 variant CENP-A that supports kinetochore assembly to enable chromosome segregation...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10208107/ https://www.ncbi.nlm.nih.gov/pubmed/36947236 http://dx.doi.org/10.1091/mbc.E22-08-0332 |