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Visualization of the three-dimensional structure of the human centromere in mitotic chromosomes by superresolution microscopy

The human centromere comprises large arrays of repetitive α-satellite DNA at the primary constriction of mitotic chromosomes. In addition, centromeres are epigenetically specified by the centromere-specific histone H3 variant CENP-A that supports kinetochore assembly to enable chromosome segregation...

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Detalles Bibliográficos
Autores principales: Di Tommaso, Elena, de Turris, Valeria, Choppakatla, Pavan, Funabiki, Hironori, Giunta, Simona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10208107/
https://www.ncbi.nlm.nih.gov/pubmed/36947236
http://dx.doi.org/10.1091/mbc.E22-08-0332