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Detecting aberrant DNA methylation in Illumina DNA methylation arrays: a toolbox and recommendations for its use

In this study, our goal was to determine probe-specific thresholds for identifying aberrant, or outlying, DNA methylation and to provide guidance on the relative merits of using continuous or outlier methylation data. To construct a reference database, we downloaded Illumina Human 450K array data fo...

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Detalles Bibliográficos
Autores principales: Downs, Bradley M., Thursby, Sara-Jayne, Cope, Leslie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10208159/
https://www.ncbi.nlm.nih.gov/pubmed/37218167
http://dx.doi.org/10.1080/15592294.2023.2213874