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Generation and characterization of infectious molecular clones of transmitted/founder HIV-1 subtype C viruses

The genetic diversity of HIV impedes vaccine development. Identifying the viral properties of transmitted/founder (T/F) variants may provide a common vaccine target. To study the biological nature of T/F viruses, we constructed full-length clones from women detected during Fiebig stage I acute HIV-1...

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Detalles Bibliográficos
Autores principales: Luthuli, Bonisile, Gounder, Kamini, Deymier, Martin J., Dong, Krista L., Balazs, Alejandro B., Mann, Jaclyn K., Ndung'u, Thumbi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10208420/
https://www.ncbi.nlm.nih.gov/pubmed/37084644
http://dx.doi.org/10.1016/j.virol.2023.04.001